Master research thesis offers:

Novel bio-inspired structures to mechanically mimic human intervertebral disc: A numerical study

Master thesis

Axis:: Structures et matériaux innovants

Site :: Lille

Type:: Master thesis

Supervising person(s):: Karim KANDIL

Context
Intervertebral disc hernia and dysfunctions are the most common health problems that affect humans. The damaged disc should often be replaced by an artificial prosthesis. For this
reason, the need of novel bio-inspired replacement systems with rational mechanically mimetic designs of the intervertebral disc is becoming increasingly mandatory and urgent.

Project description
The objective of this MSR is to design new polymer-based prostheses that can mimic the real intervertebral disc mechanical response. The mechanics of the new designs should be
controlled by tailoring the mesostructure (shape and thickness), and the material microstructure. The biomimetic capabilities of the proposed structures will be tested via numerical simulations then compared to the natural intervertebral disc conduct in terms of nonlinear stiffness and transversal behavior while considering regional dependency. Once validated in silico, the new designs could be printed using advanced 3D printing technologies and tested experimentally.

required skills:: Good knowledge of resistance of materials and mechanical design is required. Basic knowledge of numerical simulation and polymer mechanics would be a plus. A sense of organization and management of scientific data is essential.

Biomechanics; Soft tissues; Finite element computation; Bioinspired prosthesis

I apply

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